Enzymatic synthesis of sialylation substrates powered by a novel polyphosphate kinase (PPK3).

نویسندگان

  • Jozef Nahálka
  • Vladimír Pätoprstý
چکیده

Active inclusion bodies of polyphosphate kinase 3 and cytidine 5'-monophosphate kinase were combined with whole cells that co-express sialic acid aldolase and CMP-sialic acid synthetase. The biocatalytic mixture was used for the synthesis of CMP-sialic acid, which was then converted to 3'-sialyllactose by whole cells.

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عنوان ژورنال:
  • Organic & biomolecular chemistry

دوره 7 9  شماره 

صفحات  -

تاریخ انتشار 2009